
This cranberry orange muffin recipe delivers the perfect balance of sweet-tart flavors in every bite. The bright orange essence complements the pop of cranberries creating that iconic Panera bakery taste right in your own kitchen. I spent years trying to recreate these muffins and this recipe finally nails that signature taste and texture.
I discovered this recipe during the holiday season last year and it has become my go-to breakfast treat whenever we have guests. The aroma of orange zest fills the kitchen and everyone always asks for the recipe before they leave.
Ingredients
- Vegetable or canola oil: provides moisture without competing with the delicate flavors
- Granulated sugar: balances the tartness of the cranberries perfectly
- Eggs: bind everything together while adding richness
- Buttermilk: creates tenderness in the crumb
- Orange juice: amplifies the citrus flavor throughout the batter
- Vanilla extract: adds subtle warmth and depth
- Kosher salt: enhances all the flavors; use Diamond Crystal for best results
- Orange zest: provides intense citrus aroma; use organic oranges if possible
- Baking powder and baking soda: work together for the perfect rise
- All purpose flour: forms the structure; stick with a quality brand
- Fresh or frozen cranberries: bring tartness and beautiful color throughout
Step-by-Step Instructions
- Prepare Your Oven and Pan:
- Heat your oven to 425°F with the rack positioned in the upper third. Thoroughly oil a 12 cup muffin tin or line with paper liners. This high initial temperature helps create those beautiful domed tops.
- Create Your Base:
- In a large bowl whisk together the granulated sugar, eggs, and oil until completely combined and slightly thickened. The mixture should look smooth and well incorporated before moving forward.
- Add The Wet Ingredients:
- Pour in the buttermilk, orange juice, vanilla, salt, and orange zest. Whisk thoroughly until everything is fully combined. The zest will distribute throughout giving every bite citrus flavor.
- Incorporate Leavening Agents:
- Whisk in the baking powder and baking soda ensuring they're evenly distributed through the batter. This prevents any bitter spots and ensures an even rise throughout.
- Fold In Flour And Cranberries:
- Using a flexible spatula gently fold the flour and cranberries into the batter just until combined. Overmixing will develop too much gluten making tough muffins. Some small streaks of flour are fine.
- Bake With Temperature Adjustment:
- Fill muffin cups evenly and bake at 425°F for 6 to 9 minutes until they rise about 1/4 to 1/2 inch above the paper. Without opening the door reduce temperature to 350°F and continue baking 6 to 10 minutes until a toothpick comes out clean.
- Cool Properly:
- Let muffins cool in the pan for only 1 to 2 minutes then transfer to a wire rack. This prevents soggy bottoms and sides from trapped steam. Allow to cool completely before glazing.
- Glaze If Desired:
- Whisk together powdered sugar, orange juice, zest, vanilla, and salt until smooth like honey. Drizzle over completely cooled muffins and allow to set for 15 minutes before serving.

The orange zest is truly the secret ingredient here. I recommend zesting your orange directly over the bowl to capture all the essential oils that release during zesting. This simple technique amplifies the citrus flavor throughout the muffins.
Make Ahead Options
These muffins actually taste even better the day after baking as the flavors have time to meld together. Store them in an airtight container at room temperature for up to 3 days or refrigerate for up to a week. For longer storage freeze them individually wrapped in plastic then placed in a freezer bag. Thaw overnight in the refrigerator or microwave gently for a quick breakfast option.
Ingredient Substitutions
If buttermilk is unavailable add 1/2 tablespoon lemon juice or white vinegar to regular milk and let stand 5 minutes before using. For a dairy free version use almond milk with the same acidification method. Frozen cranberries work perfectly but may require slightly longer baking time. You can substitute dried cranberries in a pinch but reduce to 1 cup and soak in hot water for 10 minutes before draining and adding to the batter.
Serving Suggestions
These muffins shine as part of a breakfast or brunch spread alongside scrambled eggs and fresh fruit. For an elevated coffee break warm a muffin slightly and serve with orange infused butter; simply mix softened butter with a bit of orange zest and honey. During the holidays these make wonderful gifts presented in a decorative basket with some specialty coffee or tea.

Flavor Variations
While the classic cranberry orange combination is perfect try these variations. Replace half the cranberries with blueberries for a mixed berry version. Add 1/2 cup chopped walnuts or pecans for texture. Substitute lemon zest and juice for the orange for a brighter flavor profile. Add 1/2 teaspoon of cinnamon or cardamom to the batter for a warm spiced undertone that pairs beautifully with the fruit.
Frequently Asked Questions
- → Can I use frozen cranberries for these muffins?
Yes, you can use frozen cranberries. Simply add them directly to the batter without thawing. The muffins may require a bit more baking time—up to 35 minutes in total.
- → How do I make sure my muffins rise well?
Start by baking the muffins at 425°F for 6-9 minutes to create a quick rise, then reduce the oven temperature to 350°F to finish baking evenly.
- → What is the purpose of the orange zest?
Orange zest adds a concentrated citrus flavor, enhancing the overall taste of the muffins. Use freshly grated zest for the best results.
- → Can I omit the glaze?
Yes, the muffins are delicious on their own, but the glaze adds an extra layer of sweetness and orange flavor for those who prefer it.
- → How should I store leftover muffins?
You can store the muffins in an airtight container at room temperature for up to 3 days or freeze them for up to a month. Glaze after defrosting for best results.